|
KMID : 0191120130280111697
|
|
Journal of Korean Medical Science
2013 Volume.28 No. 11 p.1697 ~ p.1699
|
|
|
Comparison of Specific IgE Antibodies to Wheat Component Allergens in Two Phenotypes of Wheat Allergy
|
|
Nam Young-Hee
Hwang Eui-Kyung
Jin Hyun-Jung
Lee Jeong-Min
Shin Yoo-Seob
Ye Young-Min
Arantxa Palacin
Gabriel Salcedo
Lee Soo-Young
Park Hae-Sim
|
|
|
Abstract
|
|
|
|
Specific IgE to gliadin was proposed as a marker for wheat dependent exercise induced anaphylaxis, while Tri a 14 was found to induce IgE response in baker's asthma. We evaluated whether these components could be used for discriminating phenotypes of wheat allergy. Twenty-nine patients who were wheat-induced anaphylaxis and/or urticaria (n=21, group I) and baker's asthma (n=8, group II) were enrolled. The prevalence of serum specific IgE to Tri a 14 was higher in group II (25%) than in group I (4.8%), while the serum specific IgE to gliadin was significantly higher in group I (70%) than in group II (12.5%). The cutoff value for predicting the baker's asthma using the ratio of serum specific IgE to Tri a 14 to gliadin was 742.8 optical density×1,000/(kU/L) with high sensitivity and specificity. These findings suggest that Tri a 14/gliadin may be a potential marker for predicting baker's asthma.
|
|
|
KEYWORD
|
|
|
Baker's Asthma, Gliadin, Lipid Transfer Protein, Wheat
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
    
|